LYAR Suppresses Beta Interferon Induction by Targeting Phosphorylated Interferon Regulatory Factor 3

The innate immune response is vital for host defense and must be tightly controlled, but the mechanisms responsible for its negative regulation are not fully understood. The cell growth-regulating nucleolar protein LYAR was found to promote replication of multiple viruses in our previous study. Here...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Yang, Cha, Liu, Xiaokun, Cheng, Tailang, Xiao, Rong, Gao, Qingxia, Ming, Fan, Jin, Meilin, Chen, Huanchun, Zhou, Hongbo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Cellular Response to Infection
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803289/
https://ncbi.nlm.nih.gov/pubmed/31413131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00769-19
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