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Human Cytomegalovirus Induces the Interferon Response via the DNA Sensor ZBP1

Human cytomegalovirus (HCMV) is a member of the betaherpesvirus family that, unlike other herpesviruses, triggers a strong innate immune response in infected cells that includes transcription of the beta interferon gene via activation of interferon regulatory factor 3 (IRF3). IRF3 activation require...

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Detalhes bibliográficos
Main Authors: DeFilippis, Victor R., Alvarado, David, Sali, Tina, Rothenburg, Stefan, Früh, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798427/
https://ncbi.nlm.nih.gov/pubmed/19846511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01748-09
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