Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice

BACKGROUND: Despite decades of intense research efforts, actions of acute opioids are not fully understood. Increasing evidence suggests that in addition to well-documented antinociceptive effects opioids also produce paradoxical hyperalgesic and excitatory effects on neurons. However, most studies...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Yen-Chin, Berta, Temugin, Liu, Tong, Tan, Ping-Heng, Ji, Ru-Rong
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353172/
https://ncbi.nlm.nih.gov/pubmed/22444868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-19
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