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DNA Base-Calling from a Nanopore Using a Viterbi Algorithm

Nanopore-based DNA sequencing is the most promising third-generation sequencing method. It has superior read length, speed, and sample requirements compared with state-of-the-art second-generation methods. However, base-calling still presents substantial difficulty because the resolution of the tech...

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מידע ביבליוגרפי
Main Authors: Timp, Winston, Comer, Jeffrey, Aksimentiev, Aleksei
פורמט: Artigo
שפה:Inglês
יצא לאור: The Biophysical Society 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353060/
https://ncbi.nlm.nih.gov/pubmed/22677395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.009
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