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Toward detection of DNA-bound proteins using solid-state nanopores: insights from computer simulations
Through all-atom molecular dynamics simulations, we explore the use of nanopores in thin synthetic membranes for detection and identification of DNA binding proteins. Reproducing the setup of a typical experiment, we simulate electric field-driven transport of DNA-bound proteins through nanopores sm...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789251/ https://ncbi.nlm.nih.gov/pubmed/23147918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201200164 |
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