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Detection of DNA sequences using an alternating electric field in a nanopore capacitor

Molecular dynamics simulations revealed that back-and-forth motion of DNA strands through a 1-nm-diameter pore exhibits sequence-specific hysteresis that arises from the reorientation of the DNA bases in the nanopore constriction. Such hysteresis of the DNA motion results in detectable changes of th...

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Detalles Bibliográficos
Autores principales: Sigalov, Grigori, Comer, Jeffrey, Timp, Gregory, Aksimentiev, Aleksei
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588427/
https://ncbi.nlm.nih.gov/pubmed/18069865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl071890k
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