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Microscopic Mechanics of Hairpin DNA Translocation through Synthetic Nanopores

Nanoscale pores have proved useful as a means to assay DNA and are actively being developed as the basis of genome sequencing methods. Hairpin DNA (hpDNA), having both double-helical and overhanging coil portions, can be trapped in a nanopore, giving ample time to execute a sequence measurement. In...

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Bibliographic Details
Main Authors: Comer, Jeffrey, Dimitrov, Valentin, Zhao, Qian, Timp, Gregory, Aksimentiev, Aleksei
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716687/
https://ncbi.nlm.nih.gov/pubmed/19167307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.09.023
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