Targeting FGFR4 Inhibits Hepatocellular Carcinoma in Preclinical Mouse Models

The fibroblast growth factor (FGF)-FGF receptor (FGFR) signaling system plays critical roles in a variety of normal developmental and physiological processes. It is also well documented that dysregulation of FGF-FGFR signaling may have important roles in tumor development and progression. The FGFR4–...

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Detalhes bibliográficos
Main Authors: French, Dorothy M., Lin, Benjamin C., Wang, Manping, Adams, Camellia, Shek, Theresa, Hötzel, Kathy, Bolon, Brad, Ferrando, Ronald, Blackmore, Craig, Schroeder, Kurt, Rodriguez, Luis A., Hristopoulos, Maria, Venook, Rayna, Ashkenazi, Avi, Desnoyers, Luc R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352934/
https://ncbi.nlm.nih.gov/pubmed/22615798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036713
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