Reduced Mature MicroRNA Levels in Association with Dicer Loss in Human Temporal Lobe Epilepsy with Hippocampal Sclerosis

Hippocampal sclerosis (HS) is a common pathological finding in patients with temporal lobe epilepsy (TLE) and is associated with altered expression of genes controlling neuronal excitability, glial function, neuroinflammation and cell death. MicroRNAs (miRNAs), a class of small non-coding RNAs, func...

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Detalhes bibliográficos
Main Authors: McKiernan, Ross C., Jimenez-Mateos, Eva M., Bray, Isabella, Engel, Tobias, Brennan, Gary P., Sano, Takanori, Michalak, Zuzanna, Moran, Catherine, Delanty, Norman, Farrell, Michael, O’Brien, Donncha, Meller, Robert, Simon, Roger P., Stallings, Raymond L., Henshall, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352899/
https://ncbi.nlm.nih.gov/pubmed/22615744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035921
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