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Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy
Temporal lobe epilepsy is associated with large-scale, wide-ranging changes in gene expression in the hippocampus. Epigenetic changes to DNA are attractive mechanisms to explain the sustained hyperexcitability of chronic epilepsy. Here, through methylation analysis of all annotated C-phosphate-G isl...
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發表在: | Brain |
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Main Authors: | , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Oxford University Press
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408428/ https://ncbi.nlm.nih.gov/pubmed/25552301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu373 |
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