Increased Mast Cell Density and Airway Responses to Allergic and Non-Allergic Stimuli in a Sheep Model of Chronic Asthma

BACKGROUND: Increased mast cell (MC) density and changes in their distribution in airway tissues is thought to contribute significantly to the pathophysiology of asthma. However, the time sequence for these changes and how they impact small airway function in asthma is not fully understood. The aim...

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Main Authors: Van der Velden, Joanne, Barker, Donna, Barcham, Garry, Koumoundouros, Emmanuel, Snibson, Kenneth
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351402/
https://ncbi.nlm.nih.gov/pubmed/22606346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037161
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