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Increased Mast Cell Density and Airway Responses to Allergic and Non-Allergic Stimuli in a Sheep Model of Chronic Asthma

BACKGROUND: Increased mast cell (MC) density and changes in their distribution in airway tissues is thought to contribute significantly to the pathophysiology of asthma. However, the time sequence for these changes and how they impact small airway function in asthma is not fully understood. The aim...

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Hlavní autoři: Van der Velden, Joanne, Barker, Donna, Barcham, Garry, Koumoundouros, Emmanuel, Snibson, Kenneth
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351402/
https://ncbi.nlm.nih.gov/pubmed/22606346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037161
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