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Assessment of Peripheral Airway Function following Chronic Allergen Challenge in a Sheep Model of Asthma

BACKGROUND: There is increasing evidence that the small airways contribute significantly to the pathophysiology of asthma. However, due to the difficulty in accessing distal lung regions in clinical settings, functional changes in the peripheral airways are often overlooked in studies of asthmatic p...

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Detalhes bibliográficos
Main Authors: Van der Velden, Joanne, Barker, Donna, Barcham, Garry, Koumoundouros, Emmanuel, Snibson, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236205/
https://ncbi.nlm.nih.gov/pubmed/22174883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028740
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