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Low Temperature and Chemical Rescue Affect Molecular Proximity of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Epithelial Sodium Channel (ENaC)
An imbalance of chloride and sodium ion transport in several epithelia is a feature of cystic fibrosis (CF), an inherited disease that is a consequence of mutations in the cftr gene. The cftr gene codes for a Cl(−) channel, the cystic fibrosis transmembrane conductance regulator (CFTR). Some mutatio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351335/ https://ncbi.nlm.nih.gov/pubmed/22442149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332031 |
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