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Low Temperature and Chemical Rescue Affect Molecular Proximity of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Epithelial Sodium Channel (ENaC)

An imbalance of chloride and sodium ion transport in several epithelia is a feature of cystic fibrosis (CF), an inherited disease that is a consequence of mutations in the cftr gene. The cftr gene codes for a Cl(−) channel, the cystic fibrosis transmembrane conductance regulator (CFTR). Some mutatio...

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Détails bibliographiques
Auteurs principaux: Qadri, Yawar J., Cormet-Boyaka, Estelle, Rooj, Arun K., Lee, William, Parpura, Vladimir, Fuller, Cathy M., Berdiev, Bakhrom K.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351335/
https://ncbi.nlm.nih.gov/pubmed/22442149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332031
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