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Toll-like Receptor Activation of Human Cells by Synthetic Triacylated Lipid A-like Molecules
Recognition of microbial molecules by mammalian host receptors is essential to mount an immune response. Hexaacylated LPS is the prototypic example of a bacterial molecule recognized by the receptor complex TLR4/MD-2 with its lipid A moiety, whereas bacterial lipopeptides are recognized by TLR2. Her...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351317/ https://ncbi.nlm.nih.gov/pubmed/22433865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.348383 |
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