Mild-stretch mechanical ventilation upregulates toll-like receptor 2 and sensitizes the lung to bacterial lipopeptide

INTRODUCTION: Mechanical ventilation (MV) could prime the lung toward an inflammatory response if exposed to another insult such as bacterial invasion. The underlying mechanisms are not so far clear. Toll-like receptors (TLRs) allow the host to recognize selectively bacterial pathogens and in turn t...

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Main Authors: Charles, Pierre-Emmanuel, Tissières, Pierre, Barbar, Saber Davide, Croisier, Delphine, Dufour, Julien, Dunn-Siegrist, Irène, Chavanet, Pascal, Pugin, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387624/
https://ncbi.nlm.nih.gov/pubmed/21794115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10330
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