RNase H cleavage of RNA hybridized to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds.
Three types of 14-mer oligonucleotides were hybridized to human beta-globin pre-mRNA and the resultant duplexes were tested for susceptibility to cleavage by RNase H from E. coli or from HeLa cell nuclear extract. The oligonucleotides contained normal deoxynucleotides, phosphorothioate analogs alter...
Guardado en:
| Publicado en: | Nucleic Acids Res |
|---|---|
| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1989
|
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555787/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.22.9193 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|