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Visualization of a DNA-PK/PARP1 complex

The DNA-dependent protein kinase (DNA-PK) and Poly(ADP-ribose) polymerase-1 (PARP1) are critical enzymes that reduce genomic damage caused by DNA lesions. They are both activated by DNA strand breaks generated by physiological and environmental factors, and they have been shown to interact. Here, we...

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Detalhes bibliográficos
Main Authors: Spagnolo, Laura, Barbeau, Jody, Curtin, Nicola J., Morris, Edward P., Pearl, Laurence H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351162/
https://ncbi.nlm.nih.gov/pubmed/22223246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1231
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