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PARP Power: A Structural Perspective on PARP1, PARP2, and PARP3 in DNA Damage Repair and Nucleosome Remodelling
Poly (ADP-ribose) polymerases (PARP) 1-3 are well-known multi-domain enzymes, catalysing the covalent modification of proteins, DNA, and themselves. They attach mono- or poly-ADP-ribose to targets using NAD(+) as a substrate. Poly-ADP-ribosylation (PARylation) is central to the important functions o...
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| Publicado en: | Int J Mol Sci |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8150716/ https://ncbi.nlm.nih.gov/pubmed/34066057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105112 |
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