A PARP1–BRG1–SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites

Creating access to DNA double-strand break (DSB) sites in the chromatin context is an essential step during the repair process, but much remains to be determined about its regulatory mechanisms. Here, using a novel reporter cassette for simultaneous detection of homologous recombination (HR) and non...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Chen, Yu, Zhang, Haiping, Xu, Zhu, Tang, Huanyin, Geng, Anke, Cai, Bailian, Su, Tao, Shi, Jiejun, Jiang, Cizhong, Tian, Xiao, Seluanov, Andrei, Huang, Jun, Wan, Xiaoping, Jiang, Ying, Gorbunova, Vera, Mao, Zhiyong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145522/
https://ncbi.nlm.nih.gov/pubmed/31291457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz592
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