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C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome

Defects of the translation apparatus in human mitochondria are known to cause disease, yet details of how protein synthesis is regulated in this organelle remain to be unveiled. Here, we characterize a novel human protein, C7orf30 that contributes critically to mitochondrial translation and specific...

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Detalles Bibliográficos
Main Authors: Rorbach, Joanna, Gammage, Payam A., Minczuk, Michal
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351152/
https://ncbi.nlm.nih.gov/pubmed/22238376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1282
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