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The conserved interaction of C7orf30 with MRPL14 promotes biogenesis of the mitochondrial large ribosomal subunit and mitochondrial translation

Mammalian mitochondria harbor a dedicated translation apparatus that is required for the synthesis of 13 mitochondrial DNA (mtDNA)-encoded polypeptides, all of which are essential components of the oxidative phosphorylation (OXPHOS) complexes. Little is known about the mechanism of assembly of the m...

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Autori principali: Fung, Stephen, Nishimura, Tamiko, Sasarman, Florin, Shoubridge, Eric A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564531/
https://ncbi.nlm.nih.gov/pubmed/23171548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-09-0651
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