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MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome

Defects of the translation apparatus in human mitochondria are known to cause disease, yet details of how protein synthesis is regulated in this organelle remain to be unveiled. Ribosome production in all organisms studied thus far entails a complex, multistep pathway involving a number of auxiliary...

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Autors principals: Rorbach, Joanna, Boesch, Pierre, Gammage, Payam A., Nicholls, Thomas J. J., Pearce, Sarah F., Patel, Dipali, Hauser, Andreas, Perocchi, Fabiana, Minczuk, Michal
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148245/
https://ncbi.nlm.nih.gov/pubmed/25009282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-01-0014
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