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The expanding proteome of the molecular chaperone HSP90
The molecular chaperone HSP90 maintains the activity and stability of a diverse set of “client” proteins that play key roles in normal and disease biology. Around 20 HSP90 inhibitors that deplete the oncogenic clientele have entered clinical trials for cancer. However, the full extent of the HSP90-d...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3350876/ https://ncbi.nlm.nih.gov/pubmed/22421145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.19722 |
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