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The expanding proteome of the molecular chaperone HSP90
The molecular chaperone HSP90 maintains the activity and stability of a diverse set of “client” proteins that play key roles in normal and disease biology. Around 20 HSP90 inhibitors that deplete the oncogenic clientele have entered clinical trials for cancer. However, the full extent of the HSP90-d...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3350876/ https://ncbi.nlm.nih.gov/pubmed/22421145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.19722 |
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