Loading...

Viral oncoproteins target the DNA methyltransferases

Small DNA tumour viruses have evolved a number of mechanisms to drive nondividing cells into S phase. Virally encoded oncoproteins such as adenovirus E1A and human papillomavirus (HPV) E7 can bindan array of cellular proteins to override proliferation arrest. The DNA methyltransferase Dnmt1 is the m...

Full description

Saved in:
Bibliographic Details
Main Authors: Burgers, WA, Blanchon, L, Pradhan, S, de Launoit, Y, Kouzarides, T, Fuks, F
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350866/
https://ncbi.nlm.nih.gov/pubmed/16983344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209950
Tags: Add Tag
No Tags, Be the first to tag this record!