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The Oncoprotein EVI1 and the DNA Methyltransferase Dnmt3 Co-Operate in Binding and De Novo Methylation of Target DNA

EVI1 has pleiotropic functions during murine embryogenesis and its targeted disruption leads to prenatal death by severely affecting the development of virtually all embryonic organs. However, its functions in adult tissues are still unclear. When inappropriately expressed, EVI1 becomes one of the m...

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Sonraí Bibleagrafaíochta
Main Authors: Senyuk, Vitalyi, Premanand, Kavitha, Xu, Peng, Qian, Zhijian, Nucifora, Giuseppina
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112226/
https://ncbi.nlm.nih.gov/pubmed/21695170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020793
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