The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription

Expression of viral proteins causes important epigenetic changes leading to abnormal cell growth. Whether viral proteins directly target histone methyltransferases (HMTs), a key family enzyme for epigenetic regulation, and modulate their enzymatic activities remains elusive. Here we show that the E6...

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Bibliografski detalji
Glavni autori: Hsu, C-H, Peng, K-L, Jhang, H-C, Lin, C-H, Wu, S-Y, Chiang, C-M, Lee, S-C, Yu, W C Y, Juan, L-J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349118/
https://ncbi.nlm.nih.gov/pubmed/21963854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.415
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