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Viral oncoproteins target the DNA methyltransferases

Small DNA tumour viruses have evolved a number of mechanisms to drive nondividing cells into S phase. Virally encoded oncoproteins such as adenovirus E1A and human papillomavirus (HPV) E7 can bindan array of cellular proteins to override proliferation arrest. The DNA methyltransferase Dnmt1 is the m...

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Main Authors: Burgers, WA, Blanchon, L, Pradhan, S, de Launoit, Y, Kouzarides, T, Fuks, F
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350866/
https://ncbi.nlm.nih.gov/pubmed/16983344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209950
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