Synthesis and Biological Evaluation of the First Dual Tyrosyl-DNA Phosphodiesterase I (Tdp1) - Topoisomerase I (Top1) Inhibitors

Substances with dual tyrosyl-DNA phosphodiesterase I - topoisomerase I inhibitory activity in one low molecular weight compound would constitute a unique class of anticancer agents that could potentially have significant advantages over drugs that work against the individual enzymes. The present stu...

詳細記述

保存先:
書誌詳細
主要な著者: Nguyen, Trung Xuan, Morrell, Andrew, Conda-Sheridan, Martin, Marchand, Christophe, Agama, Keli, Bermingam, Alun, Stephen, Andrew G., Chergui, Adel, Naumova, Alena, Fisher, Robert, O’Keefe, Barry R., Pommier, Yves, Cushman, Mark
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350798/
https://ncbi.nlm.nih.gov/pubmed/22536944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300335n
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料