Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis

Centrioles organize the centrosome, and accurate control of their number is critical for the maintenance of genomic integrity. Centrioles duplicate once per cell cycle, and duplication is coordinated by Polo-like kinase 4 (Plk4). We previously demonstrated that Plk4 accumulation is autoregulated by...

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Bibliographic Details
Main Authors: Holland, Andrew J., Fachinetti, Daniele, Da Cruz, Sandrine, Zhu, Quan, Vitre, Benjamin, Lince-Faria, Mariana, Chen, Denaly, Parish, Nicole, Verma, Inder M., Bettencourt-Dias, Monica, Cleveland, Don W.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350549/
https://ncbi.nlm.nih.gov/pubmed/22456511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1043
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