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Cep152 interacts with Plk4 and is required for centriole duplication

Centrioles are microtubule-based structures that organize the centrosome and nucleate cilia. Centrioles duplicate once per cell cycle, and duplication requires Plk4, a member of the Polo-like kinase family; however, the mechanism linking Plk4 activity and centriole formation is unknown. In this stud...

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Detalles Bibliográficos
Main Authors: Hatch, Emily M., Kulukian, Anita, Holland, Andrew J., Cleveland, Don W., Stearns, Tim
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2983069/
https://ncbi.nlm.nih.gov/pubmed/21059850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006049
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