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The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle
Centrioles organize the centrosome, and accurate control of their number is critical for the maintenance of genomic integrity. Centriole duplication occurs once per cell cycle and is controlled by Polo-like kinase 4 (Plk4). We showed previously that Plk4 phosphorylates itself to promote its degradat...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533073/ https://ncbi.nlm.nih.gov/pubmed/23249732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.207027.112 |
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