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Glucose-6-phosphatase-β, implicated in a congenital neutropenia syndrome, is essential for macrophage energy homeostasis and functionality

Glucose-6-phosphatase-β (G6Pase-β or G6PC3) deficiency, also known as severe congenital neutropenia syndrome 4, is characterized not only by neutropenia but also by impaired neutrophil energy homeostasis and functionality. We now show the syndrome is also associated with macrophage dysfunction, with...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jun, Hyun Sik, Cheung, Yuk Yin, Lee, Young Mok, Mansfield, Brian C., Chou, Janice Y.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society of Hematology 2012
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350367/
https://ncbi.nlm.nih.gov/pubmed/22246029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-377820
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