Macrophage β(2) Integrin–Mediated, HuR-Dependent Stabilization of Angiogenic Factor–Encoding mRNAs in Inflammatory Angiogenesis

HuR is a member of the Drosophila Elav protein family that binds mRNA degradation sequences and prevents RNase-mediated degradation. Such HuR-mediated mRNA stabilization, which is stimulated by integrin engagement and is controlled at the level of HuR nuclear export, is critically involved in T-cell...

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Detalhes bibliográficos
Main Authors: Zhang, Jiange, Modi, Yasha, Yarovinsky, Timur, Yu, Jun, Collinge, Mark, Kyriakides, Themis, Zhu, Yizhun, Sessa, William C., Pardi, Ruggero, Bender, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349897/
https://ncbi.nlm.nih.gov/pubmed/22322302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.12.025
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