Targeted Deletion of Jun/AP-1 in Alveolar Epithelial Cells Causes Progressive Emphysema and Worsens Cigarette Smoke–Induced Lung Inflammation

Chronic obstructive pulmonary disease appears to occur slowly and progressively over many years, with both genetic factors and environmental modifiers contributing to its pathogenesis. Although the c-Jun/activator protein 1 transcriptional factor regulates cell proliferation, apoptosis, and inflamma...

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Detalhes bibliográficos
Main Authors: Reddy, Narsa M., Vegiraju, Suryanaraya, Irving, Ashley, Paun, Bogdan C., Luzina, Irina G., Atamas, Sergei P., Biswal, Shyam, Ana, Navas-Acien, Mitzner, Wayne, Reddy, Sekhar P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349866/
https://ncbi.nlm.nih.gov/pubmed/22265050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.10.029
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