A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics

A pro-asthmatic culture milieu and β(2)-agonist (isoproterenol) were previously shown to regulate the expression of select transcription factors (TFs) within human airway epithelial and smooth muscle cells. This study tests 1116 single nucleotide polymorphisms (SNPs) across 98 of these TF genes for...

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Autori principali: Duan, Qing Ling, Du, Rose, Lasky-Su, Jessica, Klanderman, Barbara J., Partch, Amanda B., Peters, Stephen P., Irvin, Charles G., Hanrahan, John P., Lima, John J., Blake, Kathryn V., Liggett, Stephen B., Litonjua, Augusto A., Tantisira, Kelan G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349771/
https://ncbi.nlm.nih.gov/pubmed/22212731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.56
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