A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics

A pro-asthmatic culture milieu and β(2)-agonist (isoproterenol) were previously shown to regulate the expression of select transcription factors (TFs) within human airway epithelial and smooth muscle cells. This study tests 1116 single nucleotide polymorphisms (SNPs) across 98 of these TF genes for...

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Bibliografiska uppgifter
Huvudupphovsmän: Duan, Qing Ling, Du, Rose, Lasky-Su, Jessica, Klanderman, Barbara J., Partch, Amanda B., Peters, Stephen P., Irvin, Charles G., Hanrahan, John P., Lima, John J., Blake, Kathryn V., Liggett, Stephen B., Litonjua, Augusto A., Tantisira, Kelan G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349771/
https://ncbi.nlm.nih.gov/pubmed/22212731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.56
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