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A genome-wide association study of bronchodilator response in asthmatics

Reversibility of airway obstruction in response to β(2)-agonists is highly variable among asthmatics, which is partially attributed to genetic factors. In a genome-wide association study of acute bronchodilator response (BDR) to inhaled albuterol, 534,290 single nucleotide polymorphisms (SNPs) were...

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Autori principali: Duan, Qing Ling, Lasky-Su, Jessica, Himes, Blanca E., Qiu, Weiliang, Litonjua, Augusto A., Damask, Amy, Lazarus, Ross, Klanderman, Barbara, Irvin, Charles G., Peters, Stephen P., Hanrahan, John P., Lima, John J., Martinez, Fernando D., Mauger, David, Chinchilli, Vernon M., Soto-Quiros, Manuel, Avila, Lydiana, Celedón, Juan C., Lange, Christoph, Weiss, Scott T., Tantisira, Kelan G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706515/
https://ncbi.nlm.nih.gov/pubmed/23508266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2013.5
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