A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics

A pro-asthmatic culture milieu and β(2)-agonist (isoproterenol) were previously shown to regulate the expression of select transcription factors (TFs) within human airway epithelial and smooth muscle cells. This study tests 1116 single nucleotide polymorphisms (SNPs) across 98 of these TF genes for...

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Autors principals: Duan, Qing Ling, Du, Rose, Lasky-Su, Jessica, Klanderman, Barbara J., Partch, Amanda B., Peters, Stephen P., Irvin, Charles G., Hanrahan, John P., Lima, John J., Blake, Kathryn V., Liggett, Stephen B., Litonjua, Augusto A., Tantisira, Kelan G.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349771/
https://ncbi.nlm.nih.gov/pubmed/22212731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.56
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