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Airway epithelial cells suppress T cell proliferation by an IFNγ/STAT1/TGFβ-dependent mechanism

Organ-specific regulation of immune responses relies on the exchange of information between nonimmune and immune cells. In a primary culture model of the lung airway, we demonstrate that T cell proliferation is potently inhibited by airway epithelial cells (ECs). This is mediated by activation of th...

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Bibliografski detalji
Glavni autori: Deppong, Christine M., Xu, Jian, Brody, Steven L., Green, Jonathan M.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349368/
https://ncbi.nlm.nih.gov/pubmed/22003092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00188.2011
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