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Muramyl Dipeptide Induces NOD2-Dependent Ly6C(high) Monocyte Recruitment to the Lungs and Protects Against Influenza Virus Infection

Bacterial peptidoglycan-derived muramyl dipeptide (MDP) and derivatives have long-recognized antiviral properties but their mechanism of action remains unclear. In recent years, the pattern-recognition receptor NOD2 has been shown to mediate innate responses to MDP. Here, we show that MDP treatment...

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Autors principals: Coulombe, François, Fiola, Stéphanie, Akira, Shizuo, Cormier, Yvon, Gosselin, Jean
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348889/
https://ncbi.nlm.nih.gov/pubmed/22590599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036734
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