MicroRNA-mediated conversion of human fibroblasts to neurons

Neurogenic transcription factors and evolutionarily conserved signalling pathways have been found to be instrumental in the formation of neurons(1,2). However, the instructive role of microRNAs (miRNAs) in neurogenesis remains unexplored. We recently discovered that miR-9* and miR-124 instruct compo...

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Autori principali: Yoo, Andrew S., Sun, Alfred X., Li, Li, Shcheglovitov, Aleksandr, Portmann, Thomas, Li, Yulong, Lee-Messer, Chris, Dolmetsch, Ricardo E., Tsien, Richard W., Crabtree, Gerald R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348862/
https://ncbi.nlm.nih.gov/pubmed/21753754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10323
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