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Reprogramming Human Fibroblasts to Neurons by Recapitulating an Essential MicroRNA-Chromatin Switch
The development of the vertebrate nervous system requires a switch of ATP-dependent chromatin remodeling mechanisms, which occures by substituting subunits within these complexes near cell cycle exit. This switching involves a triple negative genetic circuitry in which REST represses miR-9 and miR-1...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951511/ https://ncbi.nlm.nih.gov/pubmed/24035011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2013.07.001 |
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