Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs

Cell fate conversion generally requires reprogramming effectors to both introduce fate programs of the target cell type and erase the identity of starting cell population. Here, we reveal insights into the activity of microRNAs, miR-9/9* and miR-124 (miR-9/9*-124) as reprogramming agents that orches...

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發表在:Cell Stem Cell
Main Authors: Cates, Kitra, McCoy, Matthew J., Kwon, Ji-Sun, Liu, Yangjian, Abernathy, Daniel G., Zhang, Bo, Liu, Shaopeng, Gontarz, Paul, Kim, Woo Kyung, Chen, Shawei, Kong, Wenjun, Ho, Joshua N., Burbach, Kyle F., Gabel, Harrison W., Morris, Samantha A., Yoo, Andrew S.
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796891/
https://ncbi.nlm.nih.gov/pubmed/32961143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.08.015
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