Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs

Cell fate conversion generally requires reprogramming effectors to both introduce fate programs of the target cell type and erase the identity of starting cell population. Here, we reveal insights into the activity of microRNAs, miR-9/9* and miR-124 (miR-9/9*-124) as reprogramming agents that orches...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Cates, Kitra, McCoy, Matthew J., Kwon, Ji-Sun, Liu, Yangjian, Abernathy, Daniel G., Zhang, Bo, Liu, Shaopeng, Gontarz, Paul, Kim, Woo Kyung, Chen, Shawei, Kong, Wenjun, Ho, Joshua N., Burbach, Kyle F., Gabel, Harrison W., Morris, Samantha A., Yoo, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796891/
https://ncbi.nlm.nih.gov/pubmed/32961143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.08.015
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