Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs

Cell fate conversion generally requires reprogramming effectors to both introduce fate programs of the target cell type and erase the identity of starting cell population. Here, we reveal insights into the activity of microRNAs, miR-9/9* and miR-124 (miR-9/9*-124) as reprogramming agents that orches...

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Publicado en:Cell Stem Cell
Main Authors: Cates, Kitra, McCoy, Matthew J., Kwon, Ji-Sun, Liu, Yangjian, Abernathy, Daniel G., Zhang, Bo, Liu, Shaopeng, Gontarz, Paul, Kim, Woo Kyung, Chen, Shawei, Kong, Wenjun, Ho, Joshua N., Burbach, Kyle F., Gabel, Harrison W., Morris, Samantha A., Yoo, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796891/
https://ncbi.nlm.nih.gov/pubmed/32961143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.08.015
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