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Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts

Aging is a major risk factor in many forms of late-onset neurodegenerative disorders. The ability to recapitulate age-related characteristics of human neurons in culture will offer unprecedented opportunities to study the biological processes underlying neuronal aging. Here, we show that using a rec...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Huh, Christine J, Zhang, Bo, Victor, Matheus B, Dahiya, Sonika, Batista, Luis FZ, Horvath, Steve, Yoo, Andrew S
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067114/
https://ncbi.nlm.nih.gov/pubmed/27644593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18648
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