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Substrate-dependent millisecond domain motions in DNA polymerase β
DNA polymerase β (Pol β) is a 39 kDa enzyme that performs the vital cellular function of repairing damaged DNA. Mutations in Pol β have been linked to various cancers and these mutations further correlated with altered Pol β enzymatic activity. The fidelity of correct nucleotide incorporation into d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348416/ https://ncbi.nlm.nih.gov/pubmed/22446382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.013 |
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