Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy

Elevated aerobic glycolysis in cancer cells (the Warburg effect) may be attributed to respiration injury or mitochondrial dysfunction, but the underlying mechanisms and therapeutic significance remain elusive. Here we report that induction of mitochondrial respiratory defect by tetracycline-controll...

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Detalhes bibliográficos
Main Authors: Lu, Weiqin, Hu, Yumin, Chen, Gang, Chen, Zhao, Zhang, Hui, Wang, Feng, Feng, Li, Pelicano, Helene, Wang, Hua, Keating, Michael J., Liu, Jinsong, McKeehan, Wallace, Wang, Huamin, Luo, Yongde, Huang, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348157/
https://ncbi.nlm.nih.gov/pubmed/22589701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001326
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